Showing posts with label kejiwaan. Show all posts
Showing posts with label kejiwaan. Show all posts

Friday, January 30, 2015

10 MAKANAN PENGUSIR STRESS

Jangan anggap sepele suatu makanan, karena banyak manfaat selain untuk "energi" kita sehari-hari.

Kita sering mengalami suasana hati yang buruk (bad mood) bete, murung atau kesel. Dan makanan - makanan cepat saji (junk food) malah akan membuat kesehatan lebih buruk,dan itu pastinya akan membuat mood kita juga kian buruk.
Tapi bagaimana jika ada makanan yang sehat, dan juga dapat bertindak sebagai anti-depresan alami? Adakah makanan yang memenuhi kualifikasi ini? Berikut adalah 10 makanan terbaik, yang akan membuat Anda lebih gembira / bahagia, sekaligus membuat Anda sehat:


1. Madu

Dalam hal kesehatan, madu jauh lebih baik daripada gula biasa. Madu mengandung kaempferol dan quercetin, yang membantu untuk mencegah depresi (dan menjaga otak sehat) dengan mengurangi peradangan di otak.
Madu juga tidak akan mengirim tubuh Anda ke mode "penimbun lemak" yang biasanya dilakukan gula biasa.


2. Remis

Remis memiliki tingkat menengah sampai jumlah tinggi vitamin B12, Selenium, Yodium, protein, dan zinc, sedangkan kadar yang rendah dari remis adalah kalori dan lemak.
Yodium ini membantu, seperti yang disebutkan sebelumnya, mendukung kelenjar tiroid, yang membantu mengatur suasana hati dan berat badan, Selenium dan Zinc membantu kelenjar tiroid, juga.
Vitamin B12 membantu untuk memperkuat dan melindungi sel otak , yang menjaga otak tetap tajam (nggak pikun) dari waktu ke waktu.
Catatan: Pastikan untuk makan kerang dari budidaya daripada kerang liar, karena hal ini tidak hanya akan menguntungkan kesehatan Anda, namun kesehatan lingkungan juga.


3. Coklat murni

Coklat murni memiliki manfaat yang tidak dipunyai susu dan coklat Jerman . Coklat murni meningkatkan aliran darah ke otak, dan memberikan dorongan instan konsentrasi dan suasana hati.
Ini akan membantu Anda merasa lebih energik dan bersemangat. Namun, jangan berlebihan: The "Journal of Psychopharmacology" mengatakan bahwa semua yang Anda butuhkan adalah beberapa ons cokelat murni setiap hari untuk menuai keuntungan.


4. Asparagus

Asparagus memiliki kadar folat dan triptofan yang tinggi, menurut penelitian terbaru,Rendahnya tingkat folat dalam tubuh seseorang dikaitkan dengan depresi pada setengah dari semua kasus depresi, .
Triptofan juga digunakan oleh otak untuk membuat serotonin, yang merupakan salah satu penyebab utama suasana hati, di otak manusia dengan menstabilkan kadar neurotransmitter.
Catatan: kalkun juga merupakan sumber tryptophan.Meskipun kalkun dikenalmembuat orang mengantuk , triptofan membutuhkan kalori untuk mengaktifkan efek seperti obat penenang.

5. Telur

Telur mengandung kadar menengah sampai tinggi Seng, Vitamin B, Yodium, Omega-3 Asam Lemak, dan protein.
Telur tidak hanya dapatmembuat Anda bersemangat, telur juga dapat membuat Anda penuh kenyang lebih lama! Sebuah penelitian di tahun 2008 dalam "International Journal of Obesity" menemukan bahwa orang yang sarapan dengan telur akan lebih langsing, dibandingkan dengan mereka yang makan bagel untuk sarapan.


6. Kelapa

Terlepas dari kenyataan bahwa bahan dari kelapa yang sering ditemukan dalam makanan penutup adalah tidak sehat, kelapa memang mengandung trigliserida . Medium-chain trigliserida adalah lemak khusus yang memicu suasana hati yang lebih baik dan mempromosikan otak agar lebih sehat.
Catatan: Santan, di sisi lain, sebenarnya kurang sehat.


7. Tomat Cherry

Semua tomat memiliki substansi yang dikenal dengan likopen.Lycopene adalah antioksidan yang melawan peradangan di otak dan melindungi otak. Untuk hasil terbaik, dianjurkan juga mengkonsumsinya dengan minyak zaitun, minyak zaitun membantu untuk meningkatkan penyerapan likopen.


8. Swiss Chard

Sayuran yang jarang dipakai ini mengandung banyak magnesium. Magnesium adalah nutrisi yang merupakan bagian penting dari reaksi biokimia yang meningkatkan tingkat energi dalam tubuh manusia.
Sebuah studi tahun 2009 dalam "Australian and New Zealand Journal of Psychiatry” menemukan bahwa kadar magnesium yang lebih rendah di dalam tubuh berkaitan dengan tingkat depresi yang tinggi.


9. Kentang Biru

Kentang biru bukan benar-benar produk yang biasa ditemukan di pasar tradisonal. Namun, kentang biru memiliki antioksidan kuat yang dikenal sebagai anthocyanin; anthocyanin memberikan kualitas neuro-protektif, seperti mengurangi peradangan otak yang umumnya terkait dengan depresi, dan meningkatkan memori jangka pendek. Kelenjar tiroid Anda akan tetap terjaga, karena yodium yang ada dalam kulitnya.


10. Yogurt Yunani

Kalsium - yang sangat banyak terkandung dalam yogurt Yunani (lebih dari susu) - membantu otak kita melepaskan neurotransmitter (perangsang kebahagiaan). Yoghurt Yunani juga memiliki protein lebih dari yoghurt biasa, yang membuat penurunan berat badan lebih mudah.

Wednesday, March 20, 2013

Xanax equals Clonazepam?





klonopin is actually stronger than xanax. 









Benzodiazepine Equivalence Charts



----------------------Benzodiazepine Dose----------Comparative Time to peak plasma level------------------------Half Life
Alprazolam----------------.5------------------------------------------------1 - 2-----------------------------------------------9 - 20
Clonazepam--------------.25-----------------------------------------------1 - 4----------------------------------------------19 - 60


This chart (from the above link) looks for the equivalent dose of a given benzo to equal 5 mg of diazepam (valium).

So, you need .5mg of alprazolam (xanax) to equal 5 mg of valium, but you only need .25 mg of clonazepam (klonopin) to equal 5 mg of valium.

The klonopin is, as you said, slower in action. it takes up to 4 hours to reach full effect where the xanax will be in full effect by 2 hours at the latest. 

However, klonopin has a much longer half life than xanax, so it will stay in your system longer. The long half life of klonopin is why doctors like it. You are less likely to become addicted to it as you do not need to continually take more klonopin throughout the day to keep anxiety at bay, so you don't get into the habit of "popping pills" and you don't experience break-through anxiety. 

As for getting the same feel from klonopin as you get from xanax... there is another reason doctors prefer klonopin and that is that xanax has a mild euphoric effect that klonopin and other benzos do not have. That mild euphoria increases the chance that patients will become habituated to and possibly misuse their medication. So, basically, klonopin is actually stronger than xanax in terms of efficacy, but if what you are looking for is that mild euphoria, (which isn't what benzos are for) you can't replicate that. 




See the link below to see BENZODIAZEPINE EQUIVALENCE TABLE



Monday, March 18, 2013

Medical Uses of Cannabis and THC




Medical Uses of Cannabis and THC

General Remarks
There are marked differences in the knowledge on the medical uses of cannabis and cannabinoids in different diseases. For nausea and vomiting associated with cancer chemotherapy, anorexia and cachexia in HIV/AIDS, chronic, especially neuropathic pain, spasticity in multiple sclerosis and spinal cord injury there is strong evidence for medical benefits. For many other indications, such as epilepsy, pruritus and depression there is much less available data. However, the scientific evidence for a specific indication does not necessarily reflect the actual therapeutic potential for a given disease.

Clinical studies with single cannabinoids or whole plant preparations (smoked cannabis, cannabis extract) have often been inspired by positive anecdotal experiences of patients employing crude cannabis products. The anti-emetic, the appetite enhancing, relaxing effects, analgesia, and therapeutic use in Tourette's syndrome were all discovered in this manner. 

Incidental observations have also revealed therapeutically useful effects. This occurred in a study with patients with Alzheimer's disease wherein the primary issue was an examination of the appetite-stimulating effects of THC. Not only appetite and body weight increased, but disturbed behaviour among the patients also decreased. The discovery of decreased intraocular pressure with THC administration in the beginning of the 1970s was also serendipitous. Additional interesting indications that have not been scientifically investigated, but remain common problems in modern medicine may benefit from treatment with cannabis or cannabinoids. For this reason, surveys have been conducted questioning individuals that use cannabis therapeutically. They were conducted either as oral non-standardized interviews in the course of investigations of state or scientific institutions (House of Lords Select Committee on Science and Technology in the UK, Institute of Medicine in the USA) on the therapeutic potential of cannabis or as anonymous surveys using standardized questionnaires.


Nausea and Vomiting
Treatment of side effects associated with antineoplastic therapy is the indication for cannabinoids which has been most documented, with about 40 studies (THC, nabilone, other THC analogues, cannabis). Most trials were conducted in the 1980s. THC has to be dosed relatively highly, so that resultant side effects may occur comparatively frequently. THC was inferior to high-dose metoclopramide in one study. There are no comparisons of THC to the modern serotonin antagonists. Some recent investigations have shown that THC in low doses improves the efficacy of other antiemetic drugs if given together. In folk medicine cannabinoids are popular and are often used in other causes of nausea including AIDS and hepatitis.


Anorexia and Cachexia
An appetite enhancing effect of THC is observed with daily divided doses totalling 5 mg. When required, the daily dose may be increased to 20 mg. In a long-term study of 94 AIDS patients, the appetite-stimulating effect of THC continued for months, confirming the appetite enhancement noted in a shorter 6 week study. THC doubled appetite on a visual analogue scale in comparison to placebo. Patients tended to retain a stable body weight over the course of seven months. A positive influence on body weight was also reported in 15 patients with Alzheimer's disease who were previously refusing food. 


In many clinical trials of THC, nabilone and cannabis, a beneficial effect on spasticity caused by multiple sclerosis or spinal cord injury has been observed. Among other positively influenced symptoms were pain, paraesthesia, tremor and ataxia. In some studies improved bladder control was observed. There is also some anecdotal evidence of a benefit of cannabis in spasticity due to lesions of the brain.


There are some positive anecdotal reports of therapeutic response to cannabis in Tourette's syndrome, dystonia and tardive dyskinesia. The use in Tourette's syndrome is currently being investigated in clinical studies. Many patients achieve a modest improvement, however some show a considerable response or even complete symptom control. In some MS patients, benefits on ataxia and reduction of tremor have been observed following the administration of THC. Despite occasional positive reports, no objective success has been found in parkinsonism or Huntington disease. However, cannabis products may prove useful in levodopa-induced dyskinesia in Parkinson disease without worsening the primary symptoms.


Large clinical studies have proven analgesic properties of cannabis products. Among possible indications are neuropathic pain due to multiple sclerosis, damage of the brachial plexus and HIV infection, pain in rheumatoid arthritis, cancer pain, headache, menstrual pain, chronic bowel inflammation and neuralgias. Combination with opioids is possible.


In 1971, during a systematic investigation of its effects in healthy cannabis users, it was observed that cannabis reduces intraocular pressure. In the following 12 years a number of studies in healthy individuals and glaucoma patients with cannabis and several natural and synthetic cannabinoids were conducted. cannabis decreases intraocular pressure by an average 25-30%, occasionally up to 50%. Some non-psychotropic cannabinoids, and to a lesser extent, some non-cannabinoid constituents of the hemp plant also decrease intraocular pressure. 


The use in epilepsy is among its historically oldest indications of cannabis. Animal experiments provide evidence of the antiepileptic effects of some cannabinoids. The anticonvulsant activity of phenytoin and diazepam have been potentiated by THC. According to a few case reports from the 20th century, some epileptic patients continue to utililize cannabis to control an otherwise unmanageable seizure disorder. Cannabis use may occasionally precipitate convulsions.


Experiments examining the anti-asthmatic effect of THC or cannabis date mainly from the 1970s, and are all acute studies. The effects of a cannabis cigarette (2% THC) or oral THC (15 mg), respectively, approximately correspond to those obtained with therapeutic doses of common bronchodilator drugs (salbutamol, isoprenaline). Since inhalation of cannabis products may irritate the mucous membranes, oral administration or another alternative delivery system would be preferable. Very few patients developed bronchoconstriction after inhalation of THC.


Dependency and Withdrawal
According to historical and modern case reports cannabis is a good remedy to combat withdrawal in dependency on benzodiazepines, opiates and alcohol. For this reason, some have referred to it as a gateway drug back. In this context, both the reduction of physical withdrawal symptoms and stress connected with discontinuance of drug abuse may play a role in its observed benefits.


Psychiatric Symptoms
An improvement of mood in reactive depression has been observed in several clinical studies with THC. There are additional case reports claiming benefit of cannabinoids in other psychiatric symptoms and diseases, such as sleep disorders, anxiety disorders, bipolar disorders, and dysthymia. Various authors have expressed different viewpoints concerning psychiatric syndromes and cannabis. While some emphasize the problems caused by cannabis, others promote the therapeutic possibilities. Quite possibly cannabis products may be either beneficial or harmful, depending on the particular case. The attending physician and the patient should be open to a critical examination of the topic, and a frankness to both possibilities.


Autoimmune Diseases and Inflammation
In a number of painful syndromes secondary to inflammatory processes (e.g. ulcerative colitis, arthritis), cannabis products may act not only as analgesics but also demonstrate anti-inflammatory potential. For example, some patients employing cannabis report a decrease in their need for steroidal and nonsteroidal anti-inflammatory drugs. Moreover there are some reports of positive effects of cannabis self-medication in allergic conditions. It is as yet unclear whether cannabis products may have a relevant effects on causative processes of autoimmune diseases.


Miscellaneous, Mixed Syndromes
There are a number of positive patient reports on medical conditions that cannot be easily assigned to the above categories, such as pruritus, hiccup, ADS (attention deficit syndrome), high blood pressure, tinnitus, chronic fatigue syndrome, restless leg syndrome, and others. Several hundreds possible indications for cannabis and THC have been described by different authors. For example, 2,5 to 5 mg THC were effective in three patients with pruritus due to liver diseases. Another example is the successful treatment of a chronic hiccup that developed after a surgery. No medication was effective, but smoking of a cannabis cigarette completely abolished the symptoms.

Cannabis products often show very good effects in diseases with multiple symptoms that encompassed within the spectrum of THC effects, for example, in painful conditions that have an inflammatory origin (e.g., arthritis), or are accompanied by increased muscle tone (e.g., menstrual cramps, spinal cord injury), or in diseases with nausea and anorexia accompanied by pain, anxiety and depression, respectively (e.g. AIDS, cancer, hepatitis C). 

See clinical studies and case reports: Click here 

Sunday, March 3, 2013

Nitrazepam






Overview

Nitrazepam (Nite-raz-ep-am) is a medicine which is used in sleeping problems.
The information in this Medicine Guide for nitrazepam varies according to the condition being treated and the particular preparation used.

Your medicine

Nitrazepam should only be used at the lowest possible dose and for a maximum of up to four weeks. This will reduce the chance of tolerance, dependence and withdrawal symptoms.
Some people, in the course of taking Nitrazepam for a sleeping problem, may find that an undiagnosed psychiatric condition, such as depression, becomes apparent. People who have a psychiatric condition and who are taking Nitrazepam may experience some changes in behaviour.
It is essential to get at least seven or eight hours continuous and uninterrupted sleep after taking Nitrazepam. If you are woken before this time has passed, Nitrazepam may cause you to have some memory problems. You may have no memory of what happened from the time you were woken until the time when the effects of this medicine have worn off.
Do not share your medicine with other people. It may not be suitable for them and may harm them.
The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.
If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine is suitable for you

Nitrazepam is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.
Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:
·         are allergic or sensitive to or have had a bad reaction to benzodiazepines in the past
·         are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
·         are debilitated
·         are elderly
·         have a personality disorder
·         have a phobic or obsessional disorder
·         have abused alcohol in the past
·         have anxiety with depression
·         have been treated with Nitrazepam over a long period of time
·         have breathing problems
·         have depression
·         have had a recent loss or bereavement
·         have kidney problems
·         have liver problems
·         have lung problems
·         have misused drugs in the past
·         have myasthenia gravis
·         have organic brain syndrome
·         have psychosis
·         have sleep apnoea syndrome

Nitrazepam is not used in children.
Over time it is possible that Nitrazepam can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Nitrazepam has become unsuitable, it is important that the prescriber is contacted immediately.

Alcohol

Alcohol can interact with certain medicines.
In the case of Nitrazepam:
·         alcohol may increase the sedative effects of Nitrazepam
You must not drink any alcohol if you are taking this medicine.

Diet

Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.
In the case of Nitrazepam:
·         there are no specific foods that you must exclude from your diet when taking Nitrazepam

Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.
In the case of Nitrazepam:
·         this medicine could affect your ability to drive or operate machinery
You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.
In the case of Nitrazepam:
·         you should only take this medicine during pregnancy if your doctor thinks that you need it
·         if you become pregnant, or think you have become pregnant while taking Nitrazepam, you must contact your prescriber
·         if you take this medicine during your pregnancy, your baby may have some problems after birth. Also, if you repeatedly take this medicine during the late stages of pregnancy, your baby may come to be physically dependent on Nitrazepam. This may lead to your baby having withdrawal symptoms from Nitrazepam after birth
You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.
If the decision is that you should not have Nitrazepam, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

Breast-feeding

Certain medicines can pass into breast milk and may reach your baby through breast-feeding.
In the case of Nitrazepam:
·         women who are breast-feeding must not take this medicine
Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.
The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.
Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.
The following medicines may interact with Nitrazepam:
·         rifampicin
The following types of medicine may interact with Nitrazepam:
·         anaesthetics
·         analgesics
·         antidepressants
·         antiepileptics
·         antipsychotics
·         barbiturates
·         hydantoins
·         hypnotics
·         liver enzyme inducers
·         liver enzyme inhibitors
·         medicines that act on the central nervous system
·         sedative antihistamines
·         tranquillisers

Nitrazepam is not used in children.
Over time it is possible that Nitrazepam can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Nitrazepam has become unsuitable, it is important that the prescriber is contacted immediately.

Alcohol

Alcohol can interact with certain medicines.
In the case of Nitrazepam:
·         alcohol may increase the sedative effects of Nitrazepam
You must not drink any alcohol if you are taking this medicine.

Diet

Medicines can interact with certain foods. In some cases, this may be harmful and your prescriber may advise you to avoid certain foods.
In the case of Nitrazepam:
·         there are no specific foods that you must exclude from your diet when taking Nitrazepam

Driving and operating machinery

When taking any medicine you should be aware that it might interfere with your ability to drive or operate machinery safely.
In the case of Nitrazepam:
·         this medicine could affect your ability to drive or operate machinery
You should see how this medicine affects you before you judge whether you are safe to drive or operate machinery. If you are in any doubt about whether you should drive or operate machinery, talk to your prescriber.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.
In the case of Nitrazepam:
·         you should only take this medicine during pregnancy if your doctor thinks that you need it
·         if you become pregnant, or think you have become pregnant while taking Nitrazepam, you must contact your prescriber
·         if you take this medicine during your pregnancy, your baby may have some problems after birth. Also, if you repeatedly take this medicine during the late stages of pregnancy, your baby may come to be physically dependent on Nitrazepam. This may lead to your baby having withdrawal symptoms from Nitrazepam after birth
You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.
If the decision is that you should not have Nitrazepam, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

Breast-feeding

Certain medicines can pass into breast milk and may reach your baby through breast-feeding.
In the case of Nitrazepam:
·         women who are breast-feeding must not take this medicine
Before you have your baby you should discuss breast-feeding with your doctor or midwife. They will help you decide what is best for you and your baby based on the benefits and risks associated with this medicine. If you wish to breast-feed you should discuss with your prescriber whether there are any other medicines you could take which would also allow you to breast-feed. You should not stop this medicine without taking advice from your doctor.

Taking other medicines

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.
The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.
Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.
The following medicines may interact with Nitrazepam:
·         rifampicin
The following types of medicine may interact with Nitrazepam:
·         anaesthetics
·         analgesics
·         antidepressants
·         antiepileptics
·         antipsychotics
·         barbiturates
·         hydantoins
·         hypnotics
·         liver enzyme inducers
·         liver enzyme inhibitors
·         medicines that act on the central nervous system
·         sedative antihistamines
·         tranquillisers
If you are taking Nitrazepam and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Complementary preparations and vitamins

Medicines can interact with complementary preparations and vitamins. In general, there is not much information available about interactions between medicines and complementary preparations or vitamins.
If you are planning to take or are already taking any complementary preparations and vitamins you should ask your prescriber whether there are any known interactions with Nitrazepam.
Your prescriber can advise whether it is appropriate for you to take combinations that are known to interact. They can also discuss with you the possible effect that the complementary preparations and vitamins may have on your condition.
If you experience any unusual effects while taking this medicine in combination with complementary preparations and vitamins, you should tell you’re prescriber.


Side-effects

A medicine is only made available to the public if the clinical trials have shown that the benefits of taking the medicine outweigh the risks.
Once a medicine has been licensed, information on the medicine's effects, both intended and unintended, is continuously recorded and updated.
Some side-effects may be serious while others may only be a mild inconvenience.
Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine, or whether you will have any side-effects at all. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine.
The frequency of these side-effects is unknown
  • balance or coordination problems
  • behavioural problems seek medical advice if you develop symptoms of depression including suicidal tendencies, paradoxical aggressive outbursts, rages, inappropriate behaviour, excitement, confusion, restlessness, agitation, irritability, delusions, nightmares, hallucinations, psychoses or other behavioural problems
  • blood and bone marrow problems
  • changes in libido
  • confusion
  • daytime sedation
  • dose tolerance
  • double vision
  • eye or eyesight problems
  • failure of Nitrazepam to achieve the intended medical effect - if Nitrazepam is repeatedly used for a few weeks
  • feeling dizzy
  • feeling emotionally numb
  • gastrointestinal problems
  • headaches
  • hypersensitivity reactions including rash, angioedema and high blood pressure
  • jaundice
  • lowered blood pressure
  • memory problems - these may lead to behavioural changes
  • muscle weakness
  • precipitation of suicide in people with depression
  • psychological problems
  • reduced alertness
  • relaxed muscles - this may lead to an increased risk of falling or hip fractures. You should be careful when moving around after you have taken Nitrazepam
  • side effects that may occur if Nitrazepam is taken at a high dose for long period of time. These may include physical and physiological dependence which may lead to drug abuse
  • skin rash or rashes
  • tiredness
  • uncovering depression
  • urinary retention
  • vertigo
  • withdrawal symptoms or rebound phenomena can occur when this medicine is stopped. These include depression, headaches, muscle weakness, nervousness, anxiety, tension, restlessness, confusion, convulsion, mood changes, rebound insomnia, psychotic-like behaviour, irritability, sweating and diarrhoea. If withdrawal is severe the following may occur: derealisation, depersonalisation, numbness, over-sensitive hearing and tingling of the extremities, hypersensitivity to light, noise and physical contact, hallucinations or seizures
Source: http://www.nhs.uk